Tapahtumakalenteri

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Dissertation: Julia Niskanen

​Julia Niskanen, University of Helsinki, Faculty of Medicine, Doctoral Programme in Integrative Life Science
The genetic background of five canine models of rare human disease

Opponent: professor Johanna Schleutker, University of Turku



Aloitusaika: 26.08.2022 12:15
Lopetusaika: 26.08.2022 14:00
Kesto: 1 hour 45 minutes
Sijainti: Porthania PII, Yliopistonkatu 3, Helsinki
Tyyppi: Dissertation
Organisaatio: UH, Faculty of Medicine
Yhteyshenkilö: julia.niskanen@helsinki.fi
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Dissertation: Jenni Liikanen

​Jenni Liikanen, University of Helsinki, Faculty of Medicine, Doctoral Program in Clinical Research
PROGNOSTIC FACTORS OF pT1 BREAST CANCER

Opponent: Professor Gábor Cserni, University of Szeged


Aloitusaika: 26.08.2022 12:15
Lopetusaika: 26.08.2022 14:00
Kesto: 1 hour 45 minutes
Sijainti: HUS Puistosairaala, Niilo Hallman sali, Stenbäckinkatu 11
Tyyppi: Dissertation
Organisaatio: UH, Faculty of Medicine
Yhteyshenkilö: jenni.s.liikanen@gmail.com
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Dissertation: Paavo Häppölä

​Paavo Häppölä, University of Helsinki, Faculty of Medicine, Doctoral Program in Population Health
Translating genetic epidemiology to health applications with large-scale biobank data

Opponent: Docent Patrik Magnusson, Karolinska Institutet



Aloitusaika: 26.08.2022 13:00
Lopetusaika: 26.08.2022 15:00
Kesto: 2 hours
Sijainti: Biomedicum1, lecture hall 2, Haartmaninkatu 8, 00290 Helsinki
Tyyppi: Dissertation
Organisaatio: UH, Faculty of Medicine
Yhteyshenkilö: paavo.happola@helsinki.fi
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HiLIFE Webinar/ Biomedicum Helsinki seminar: Julia TCW

Cholesterol and matrisome pathways dysregulated in astrocytes and microglia

Dr. Julia TCW is an assistant professor at Boston University (primary appointment at Department of Pharmacology & Experimental therapeutics) and a director of the Laboratory of Human Induced Pluripotent Stem Cell Therapeutics. She received Ph.D. and A.M. in Molecular and Cellular Biology from Harvard University with Biophysics training background and research studies in induced pluripotent stem cell (iPSC) reprogramming in the Department of Stem Cell and Regenerative Biology. She then perused her postdoctoral research in the Department of Neuroscience, Ronald M. Loeb Center for Alzheimer’s Disease, Department of Genetics and Genomic Sciences at Icahn School of Medicine at Mount Sinai, New York, with a research focus of the development of iPSC models and study Alzheimer’s disease (AD) genetics. Currently, the TCW laboratory is aiming at human induced pluripotent stem cell therapeutics for AD and neurodegenerative diseases.  

Welcome to this exciting seminar!  

Liisa Myllykangas 


Selected publications: 

TCW J#, Qian L, Pipalia NH, Chao MJ, Liang SA, Shi Y, Jain B.R., Bertelsen SE, Kapoor M, Marcora E, Sikora E, Andrews EJ, Martini AC, Karch, CM, Head E, Holtzman DM, Zhang B, Wang M, Maxfield FR, Poon WW, Goate AM. Cholesterol and matrisome pathways dysregulated in astrocytes and microglia. Cell, Jun, 2022. https://www.cell.com/cell/pdf/S0092-8674(22)00648-1.pdf 

TCW J*, Preman P*, Snellinx A, Calafate S, Alfonso-Triguero M, Corthout N, Munck S, Rudolf Thal D, Goate AM, De Strooper B, Arranz AM. Human iPSC-derived astrocytes transplanted into the mouse brain undergo morphological changes in response to amyloid-β plaques. Molecular Neurodegeneration. 2021;16:68. *Co-first authors PMID: 34563212 PMCID: PMC8467145. https://molecularneurodegeneration.biomedcentral.com/articles/10.1186/s13024-021-00487-8 

Saroja SR, Gorbachev K, TCW J, Goate AM, Pereira AC. Astrocyte-secreted glypican-4 drives APOE4-dependent tau hyperphosphorylation. PNAS, Jul, 2022. https://www.pnas.org/doi/10.1073/pnas.2108870119 



Aloitusaika: 29.08.2022 13:00
Lopetusaika: 29.08.2022 14:00
Kesto: 1 hour
Sijainti: Biomedicum1, lecture hall 3, Haartmaninkatu 8, 00290 Helsinki
Tyyppi: Seminar
Organisaatio: Biomedicum Helsinki
Yhteyshenkilö: hilife-seminars@helsinki.fi
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Dissertation: Risto Halonen

​Risto Halonen, University of Helsinki, Faculty of Medicine, Doctoral Programme Brain and Mind

Sleep and its oscillatory characteristics in overnight learning - what is the role of plasticity genes BDNF and COMT?
Professor Björn Rasch, University of Fribourg

Aloitusaika: 30.08.2022 13:00
Lopetusaika: 30.08.2022 15:00
Kesto: 2 hours
Sijainti: University of Helsinki main building, Fabianinkatu 33, Helsinki
Tyyppi: Dissertation
Organisaatio: UH, Faculty of Medicine
Yhteyshenkilö: risto.halonen@helsinki.fi