Tapahtumakalenteri

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KLIINISEN PATOLOGIAN NYKYNÄKYMIÄ: Ari Ristimäki

​Vaikeat polyypit suolessa

Ari Ristimäki


Aloitusaika: 14.02.2023 12:15
Lopetusaika: 14.02.2023 13:00
Kesto: 45 minutes
Sijainti: Patologian kirjasto (C-porras, 2. krs), Haartmaninkatu 3, 00290 Helsinki
Tyyppi: Seminar
Organisaatio: UH, Faculty of Medicine
Yhteyshenkilö:
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Kliinisen kemian seminaarit: Hanna Jarva

Immunologiset tutkimukset
H
anna Jarva
Aloitusaika: 14.02.2023 14:15
Lopetusaika: 14.02.2023 15:00
Kesto: 45 minutes
Sijainti: HUSLAB talo, Topeliuksenkatu 32, 7krs, kokoushuone Kurki G7401
Tyyppi: Seminar
Organisaatio: UH, Faculty of Medicine
Yhteyshenkilö: tuukka.helin@helsinki.fi
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Wihuri Research Institute Special Seminar by Dr. Paolo Tammaro

​Mechanisms of control of cerebral blood flow in health and disease by the TMEM16A chloride channel


Dr. Paolo Tammaro’s lab’s research interests lie in understanding the molecular mechanisms that regulate the function of vascular ion channels and in identifying new ion channel targets and specific compounds with the goal of modulating blood vessel function for therapeutic benefit. His most recent work focuses on the role of chloride transport mechanisms in the control of the function of pericytes (contractile cells that surround capillaries) in regulation of cerebral blood flow after ischemia. The results suggest that this channel constitutes a key contractile mechanism in cerebral pericytes, where it may constitute a new drug target for disease of altered microvascular blood flow such as stroke and vascular dementia.

 

https://www.pharm.ox.ac.uk/research/groups/tammaro-group-molecular-and-systems-pharmacology-of-vascular-ion-channels

 

Selected publications:

 

The Ca2+-gated channel TMEM16A amplifies capillary pericyte contraction and reduces cerebral blood flow after ischemia. Korte N, Ilkan Z, Pearson CL, Pfeiffer T, Singhal P, Rock JR, Sethi  H, Gill D, Attwell D, Tammaro P. J Clin Invest. (2022) 132:e154118. doi: 10.1172/JCI154118.

 

An outer-pore gate modulates the pharmacology of the TMEM16A channel. Dinsdale RL, Pipatpolkai T, Agostinelli E, Russell AJ, Stansfeld PJ, Tammaro P. Proc Natl Acad Sci U S A. (2021) 118(34):e2023572118. doi: 10.1073/pnas.2023572118.

 

Ion channels as convergence points in the pathology of pulmonary arterial hypertension.

Jouen-Tachoire TRH, Tucker SJ, Tammaro P. Biochem Soc Trans. (2021) 49(4):1855-1865. doi: 10.1042/BST20210538.

 

Please contact Pipsa Saharinen (pipsa.saharinen@helsinki.fi) for an appointment with the speaker.


Aloitusaika: 14.02.2023 14:15
Lopetusaika: 14.02.2023 15:15
Kesto:
Sijainti: Biomedicum1, lecture hall 3, Haartmaninkatu 8, 00290 Helsinki
Tyyppi: Seminar
Organisaatio: Wihurin tutkimuslaitos
Yhteyshenkilö: pipsa.saharinen@helsinki.fi
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iCAN science semiar: Coleman Lindsley

​Germline predisposition to myeloid malignancies: biology and clinical implications.
prof. Coleman Lindsley Dana-Farber Cancer Insitute, Boston

Aloitusaika: 15.02.2023 12:00
Lopetusaika: 15.02.2023 13:00
Kesto:
Sijainti: Biomedicum 1, seminar room 1-2
Tyyppi: Seminar
Organisaatio: iCAN Flagship Team
Yhteyshenkilö: ican@helsinki.fi
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Biostatistics drop-in workshop

Are you a researcher needing support with any statistical aspect of your work? The Biostatistics Consulting Service here at Meilahti Campus holds drop-in workshop sessions every other week to answer smaller questions about your analysis - solving a particular problem, how to get started, etc. We provide service in Finnish, English and Swedish.

 

The next workshop is on Wednesday 15th February, at 13:00-15:00 in Biomedicum 2B, in the Olohuone on floor 6. Come whenever you can. Note that you may end up waiting a while for your turn, especially early on in the session. We aim to spend no more than 15 minutes with each customer.

 

Bring: 

·       your computer

·       your data

·       your questions

and we biostatisticians will be on hand to help and guide.

 

Registration is not required, but you can help us prepare for your questions by filling in this form. The workshops are open to any researcher at the university's Medical Faculty, HUS or FIMM.

 

The next sessions are planned for 1.3, 15.3, 29.3, 12.4, 26.4, 10.5, and 24.5. For more in-depth questions, please book a one-on-one consultation session using this e-form where we will have time to go into more detail.

 


Aloitusaika: 15.02.2023 13:00
Lopetusaika: 15.02.2023 15:00
Kesto: 2 hours
Sijainti: Biomedicum 2, 6th floor lounge
Tyyppi: Course
Organisaatio: Biostatistics Consulting Service
Yhteyshenkilö: biostat-consult@helsinki.fi