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Dissertation: Juulia Lantto

​Juulia Lantto, Faculty of Medicine, Doctoral Programme in Clinical Research

Opponent: Professor Giancarlo Mari, Department of Obstetrics and Gynecology, Cleveland Clinic, Cleveland, Ohio, USA

Aloitusaika: 21.05.2021 15:00
Lopetusaika: 21.05.2021 17:00
Kesto: 2 hours
Sijainti: remotely
Tyyppi: Dissertation
Organisaatio: UH, Faculty of Medicine
Yhteyshenkilö: juulia.lantto@fimnet.fi
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CancerBio Summer School Special Seminar: Mikala Egeblad

Heroes and villains: Immune cells regulating metastasis

Professor Mikala Egeblad obtained degrees in Medicine (B.S., 1993). Human Biology (M.Sc., 1996), and in Cancer Biology (Ph.D., 2000) from the University of Copenhagen, Denmark. She did her dissertation research under the mentorship of Dr. Marja Jäättelä at The Danish Cancer Society. Her postdoctoral training was performed in the laboratory of Dr. Zena Werb at University of California, San Francisco. There, she began developing intravital spinning disk confocal microscopy to understand how the microenvironment influences tumor progression, focusing on innate immune cell responses and protease-mediated extracellular matrix remodeling. She came to Cold Spring Harbor Laboratory in 2009 and established a research group that studies how the tumor microenvironment contributes to therapy resistance and metastasis, primarily focusing on the role of inflammatory cells. In 2014, she was promoted to Associate Professor and in January 2021 to Professor.

Selected publications:

Sun, L., Kees, T., Almeida, A. S., Liu, B., ... and Egeblad, M. (2020). Activating a collaborative innate-adaptive immune response to control breast and ovarian cancer metastasis. bioRxiv, 2020/200477; https://doi.org/10.1101/2020.07.13.200477

Fein, M. R., He, X. Y., Almeida, A. S., Bruzas, E., ... and Egeblad, M. (2020). Cancer cell CCR2 orchestrates suppression of the adaptive immune response. Journal of Experimental Medicine. https://doi.org/10.1084/JEM.20181551  

Middleton, EA, He, X.-Y., Denorme, F, Campbell, RA, … and Egeblad, M., Schiffman, JD., Con Yost, C. (2020). Neutrophil Extracellular Traps (NETs) Contribute to Immunothrombosis in COVID-19 Acute Respiratory Distress Syndrome. Blood. https://doi.org/10.1182/blood.2020007008

Barnes, B. J., Adrover, J. M., Baxter-Stoltzfus, A., Borczuk, A., … and Egeblad, M. (2020). Targeting potential drivers of COVID-19: Neutrophil extracellular traps. In Journal of Experimental Medicine. https://doi.org/10.1084/jem.20200652

Albrengues, J., Shields, M. A., Ng, D., Park, C. G., Ambrico, A., … and Egeblad, M. (2018). Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice. Science. https://doi.org/10.1126/science.aao4227

Park, J., Wysocki, R. W., Amoozgar, Z., Maiorino, L., ... and Egeblad, M. (2016). Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps. Science Translational Medicine. https://doi.org/10.1126/scitranslmed.aag1711

Find below more information on Professor Egeblad’s research and recent publications:

We welcome you to this exciting seminar.
CancerBio Summer School organizing team

Juha Klefström, Jeroen Pouwels,
Mariel Savelius, Krista Tuohinto,
Dipabarna Bhattacharya & Anna Laury

Aloitusaika: 24.05.2021 15:00
Lopetusaika: 24.05.2021 16:00
Sijainti: remotely
Tyyppi: Webinar
Organisaatio: CancerBio Summer School
Yhteyshenkilö: mariel.savelius@helsinki.fi>
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Dissertation Miia Seppälä

​Miia Seppälä, Faculty of Medicine, Doctoral Programme in Biomedicine
Prognostics markers in mobile tongue and tongue base squamous cell carcinoma

Opponent: docent Heikki Irjala, University of Turku

Aloitusaika: 26.05.2021 13:00
Lopetusaika: 26.05.2021 15:00
Kesto: 2 hours
Sijainti: remotely
Tyyppi: Dissertation
Organisaatio: UH, Faculty of Medicine
Yhteyshenkilö: miia.seppala@helsinki.fi
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Dissertation: Shady Awad

Shady Awad, Faculty of Medicine, Doctoral Programme in Clinical Research

​Interative genomic and drug sensitivity profiling of High-Risk Chronic Myeloid Leukemia Patients in the Context of Personalized Medicine

Opponent: Professor Oliver Hantschel, Philipps-University Marburg

Aloitusaika: 27.05.2021 12:00
Lopetusaika: 27.05.2021 14:00
Kesto: 1 hour
Sijainti: remotely
Tyyppi: Dissertation
Organisaatio: UH, Faculty of Medicine
Yhteyshenkilö: shady.awad@helsinki.fi
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Dissertation Elina Parri

​Elina Parri, Faculty of Biological and Environmental sciences, Doctoral Programme in Biomedicine
Targeting STAT3 and kinases in lymphoid malignancies

Opponent: Professor Veronika Sexl, Institute of Pharmacology and Toxicology, University of Veterinary Medicine, Vienna, Austria

Aloitusaika: 27.05.2021 13:00
Lopetusaika: 27.05.2021 15:00
Kesto: 2 hours
Sijainti: remotely
Tyyppi: Dissertation
Organisaatio: UH, Faculty of Bioogical and Environmental Sciences
Yhteyshenkilö: elina.parri@helsinki.fi