Tapahtumakalenteri

Kevin P. Campbell, Ph.D., is an investigator with the Howard Hughes Medical Institute, Director of the Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Center, and Chair, Department of Molecular Physiology and Biophysics at the Carver College of Medicine, University of Iowa. He is widely recognized for his fundamental contributions to neuromuscular disease research. His work has led to the identification of the molecular and genetic basis of several forms of muscular dystrophy and has provided a clearer understanding of muscular dystrophy disease processes. Campbell discovered dystroglycan and elucidated its function as an extracellular matrix receptor. He established that dystroglycan is involved in a variety of physiological and developmental processes, including maintenance of skeletal muscle function as well as formation and function of the central nervous system. He showed that complex post-translational processing of dystroglycan, including extensive glycosylation, is required for its ability to function as an extracellular matrix receptor and that abnormal glycosylation results in a variety of congenital and limb-girdle muscular dystrophies with or without associated defects in brain development and function. Campbell's findings have already greatly improved the diagnosis of muscular dystrophy, and they point to strategies for developing therapies for these devastating inherited neuromuscular diseases. 

Campbell Research Group