Tapahtumakalenteri

elokuu 11

Special seminar: Kerry Fisher

Targeting stromal-rich cancers with oncolytic viruses

Associated professor Kerry Fisher, Department of Oncology, University of Oxford

The seminar is hosted by Professor Akseli Hemminki.

 

Associated professor Kerry Fisher’s research interests include oncolytic viruses, tumour microenvironment and metabolism. Several oncolytic candidates developed by his group are currently undergoing evaluation in phase I/II clinical trials. He is also a director of the human tissue facility in the Department of Oncology, University of Oxford. The purpose of the human tissue facility is to bridge the translational gap for advanced therapies and biologics being positioned for clinical trials.

 

Selected publications:

 

1. Fisher K, Hazini A, Seymour LW. Tackling HLA Deficiencies Head on with Oncolytic Viruses. Cancers 2021, 13, 719. 2021.

2. Hill C, Grundy M, Bau L, Wallington S, Balkaran J, Ramos V, Fisher K, Seymour L, Coussios C, Carlisle R. Polymer stealthing and mucin-1 retargeting for enhanced pharmacokinetics of an oncolytic vaccinia virus. Molecular Therapy-Oncolytics 2021.

3. Pokrovska TD, Jacobus EJ, Puliyadi R, Prevo R, Frost S, Dyer A, Baugh R, Rodriguez-Berriguete G, Fisher K, Granata G. External beam radiation therapy and enadenotucirev: inhibition of the DDR and mechanisms of radiation-mediated virus increase. Cancers 2020; 12(4): 798. Currently in clinical trial (NCT03916510 and completed NCT02053220)

4. O’Cathail SM, Davis S, Holmes J, Brown R, Fisher K, Seymour L, Adams R, Good J, Sebag-Montefiore D, Maughan T. A phase 1 trial of the safety, tolerability and biological effects of intravenous Enadenotucirev, a novel oncolytic virus, in combination with chemoradiotherapy in locally advanced rectal cancer (CEDAR). Radiation Oncology 2020; 15(1): 1-8.

5. Leung EYL, Ennis DP, Kennedy PR, Hansell C, Dowson S, Farquharson M, Spiliopoulou P, Nautiyal J, McNamara S, Carlin LM, Fisher K, Davis DM, Graham G, McNeish IA. NK Cells Augment Oncolytic Adenovirus Cytotoxicity in Ovarian Cancer. Mol Ther Oncolytics 2020; 16: 289-301.

6. Dyer A, Frost S, Fisher K, Seymour L. The role of cancer metabolism in defining the success of oncolytic viro-immunotherapy. Cytokine & Growth Factor Reviews 2020.

7. Francini N, Cochrane D, Illingworth S, Purdie L, Mantovani G, Fisher K, Seymour LW, Spain SG, Alexander C. Polyvalent diazonium polymers provide efficient protection of oncolytic adenovirus enadenotucirev from neutralizing antibodies while maintaining biological activity in vitro and in vivo. Bioconjugate chemistry 2019; 30(4): 1244-57.

 

Welcome to this exciting seminar!

 



Aloitusaika: 11.08.2023 09:00
Lopetusaika: 11.08.2023 10:00
Kesto:
Sijainti: Biomedicum 1, meeting room 8-9
Tyyppi: Seminar
Organisaatio: UH, Faculty of Medicine
Yhteyshenkilö: minna.k.oksanen@helsinki.fi
elokuu 11

Dissertation: Pushpa Khanal

Pushpa Khanal, University of Helsinki, Faculty of Biological and Environmental Sciences, Doctoral Programme Brain and Mind
Molecular Regulation of the Dendritic Spine Initiation

Opponent: Professor Martin Korte, Technische Universität Braunschweig, Germany



Aloitusaika: 11.08.2023 12:00
Lopetusaika: 11.08.2023 14:00
Kesto: 2 hours
Sijainti: Biomedicum1, lecture hall 2, Haartmaninkatu 8, 00290 Helsinki
Tyyppi: Dissertation
Organisaatio: UH, Faculty of Medicine
Yhteyshenkilö: pushpa.khanal@helsinki.fi
elokuu 11

Dissertation: Dafne Quixabeira

Dafne Quixabeira, University of Helsinki, Faculty of Medicine, Doctoral Program in Clinical Research
Facilitating cancer immunotherapies with armed oncolytic adenoviruses

Opponent: PhD, Associate Professor Kerry Fisher, University of Oxford



Aloitusaika: 11.08.2023 13:00
Lopetusaika: 11.08.2023 15:00
Kesto: 2 hours
Sijainti: Haartman Institute, lecture hall 1, Haartmaninkatu 3, 00290 Helsinki
Tyyppi: Dissertation
Organisaatio: UH, Faculty of Medicine
Yhteyshenkilö: dafne.quixabeira@helsinki.fi
elokuu 16

Biostatistics drop-in workshop

​Are you a researcher needing support with any statistical aspect of your work? The Biostatistics Consulting Service here at Meilahti Campus holds drop-in workshop sessions every other week to answer smaller questions about your analysis - solving a particular problem, how to get started, etc. We provide service in Finnish, English and Swedish.

 

The next workshop is on Wednesday 16th August, at 13:00-15:00 in Biomedicum 2B, in the Olohuone on floor 6. Come whenever you can. Note that you may end up waiting a while for your turn, especially early on in the session. We aim to spend no more than 15 minutes with each customer.

 

Bring: 

·       your computer

·       your data

·       your questions

and we biostatisticians will be on hand to help and guide. 

 

Registration is not required, but you can help us prepare for your questions by filling in this form. The workshops are open to any researcher at the university's Medical Faculty, HUS or FIMM. 

The autumn's following sessions are planned for 30.8, 13.9, 27.9, 11.10, 25.10, 8.11, 22.11 & 13.12 (not 6.12!).

For more in-depth questions, please book a one-on-one consultation session using this e-form where we will have time to go into more detail. 

 

From the Biostatistics Team

Aloitusaika: 16.08.2023 13:00
Lopetusaika: 16.08.2023 15:00
Kesto: 2 hours
Sijainti: Biomedicum 2, 6th floor lounge
Tyyppi: Other
Organisaatio: Biostatistics Consulting Service
Yhteyshenkilö: biostat-consult@helsinki.fi
elokuu 18

Kliinisen mikrobiologian perjantaisarja: Anu Pätäri-Sampo

Mitä bakteerien herkkyysvastaukset kertovat lääkärille? 
Anu Pätäri-Sampo, LT, kliinisen mikrobiologian erikoislääkäri, osastonylilääkäri, HUS Diagnostiikkakeskus


Opetusnäyte dosentuuria varten (20 min + 10 min)


Aloitusaika: 18.08.2023 12:00
Lopetusaika: 18.08.2023 13:00
Kesto:
Sijainti: HUSLAB-talo, 7krs, Johtokunnan kokoushuone
Tyyppi: Docententship lecture
Organisaatio: HUS
Yhteyshenkilö: kira.virtanen@hus.fi