Tapahtumakalenteri (vanha)
Special seminar: Kerry Fisher
Associated professor Kerry Fisher, Department of Oncology, University of Oxford
The seminar is hosted by Professor Akseli Hemminki.
Associated professor Kerry Fisher’s research interests include oncolytic viruses, tumour microenvironment and metabolism. Several oncolytic candidates developed by his group are currently undergoing evaluation in phase I/II clinical trials. He is also a director of the human tissue facility in the Department of Oncology, University of Oxford. The purpose of the human tissue facility is to bridge the translational gap for advanced therapies and biologics being positioned for clinical trials.
Selected publications:
1. Fisher K, Hazini A, Seymour LW. Tackling HLA Deficiencies Head on with Oncolytic Viruses. Cancers 2021, 13, 719. 2021.
2. Hill C, Grundy M, Bau L, Wallington S, Balkaran J, Ramos V, Fisher K, Seymour L, Coussios C, Carlisle R. Polymer stealthing and mucin-1 retargeting for enhanced pharmacokinetics of an oncolytic vaccinia virus. Molecular Therapy-Oncolytics 2021.
3. Pokrovska TD, Jacobus EJ, Puliyadi R, Prevo R, Frost S, Dyer A, Baugh R, Rodriguez-Berriguete G, Fisher K, Granata G. External beam radiation therapy and enadenotucirev: inhibition of the DDR and mechanisms of radiation-mediated virus increase. Cancers 2020; 12(4): 798. Currently in clinical trial (NCT03916510 and completed NCT02053220)
4. O’Cathail SM, Davis S, Holmes J, Brown R, Fisher K, Seymour L, Adams R, Good J, Sebag-Montefiore D, Maughan T. A phase 1 trial of the safety, tolerability and biological effects of intravenous Enadenotucirev, a novel oncolytic virus, in combination with chemoradiotherapy in locally advanced rectal cancer (CEDAR). Radiation Oncology 2020; 15(1): 1-8.
5. Leung EYL, Ennis DP, Kennedy PR, Hansell C, Dowson S, Farquharson M, Spiliopoulou P, Nautiyal J, McNamara S, Carlin LM, Fisher K, Davis DM, Graham G, McNeish IA. NK Cells Augment Oncolytic Adenovirus Cytotoxicity in Ovarian Cancer. Mol Ther Oncolytics 2020; 16: 289-301.
6. Dyer A, Frost S, Fisher K, Seymour L. The role of cancer metabolism in defining the success of oncolytic viro-immunotherapy. Cytokine & Growth Factor Reviews 2020.
7. Francini N, Cochrane D, Illingworth S, Purdie L, Mantovani G, Fisher K, Seymour LW, Spain SG, Alexander C. Polyvalent diazonium polymers provide efficient protection of oncolytic adenovirus enadenotucirev from neutralizing antibodies while maintaining biological activity in vitro and in vivo. Bioconjugate chemistry 2019; 30(4): 1244-57.
Welcome to this exciting seminar!
Dissertation: Pushpa Khanal
Opponent: Professor Martin Korte, Technische Universität Braunschweig, Germany
Dissertation: Dafne Quixabeira
Opponent: PhD, Associate Professor Kerry Fisher, University of Oxford
Biostatistics drop-in workshop
The next workshop is on Wednesday 16th August, at 13:00-15:00 in Biomedicum 2B, in the Olohuone on floor 6. Come whenever you can. Note that you may end up waiting a while for your turn, especially early on in the session. We aim to spend no more than 15 minutes with each customer.
Bring:
· your computer
· your data
· your questions
and we biostatisticians will be on hand to help and guide.
Registration is not required, but you can help us prepare for your questions by filling in this form. The workshops are open to any researcher at the university's Medical Faculty, HUS or FIMM.
The autumn's following sessions are planned for 30.8, 13.9, 27.9, 11.10, 25.10, 8.11, 22.11 & 13.12 (not 6.12!).
For more in-depth questions, please book a one-on-one consultation session using this e-form where we will have time to go into more detail.
From the Biostatistics Team
Kliinisen mikrobiologian perjantaisarja: Anu Pätäri-Sampo
Anu Pätäri-Sampo, LT, kliinisen mikrobiologian erikoislääkäri, osastonylilääkäri, HUS Diagnostiikkakeskus
Opetusnäyte dosentuuria varten (20 min + 10 min)