Events
Dissertation: Moon Hee Lee
Opponent: Docent Jussi Koivunen, University of Oulu and Oulu University Hospital
EVOMET Metastasis expansion and drug resistance workshop
Host: Sakari Vanharanta
Dissertation: Pauliina Kallio
TRIMM and iCAN seminar: Dr Lélia Delamarre
Director & Distinguished Scientist of Cancer Immunology at Genentech, San Francisco, Dr Lélia Delamarre will give a seminar on
Cancer Vaccines: potential and challenges
Lélia's laboratory is dedicated to investigate innovative methods for enhancing anti-tumor T cell responses through priming. Currently, their research has shifted towards identifying tumor antigens that influence immune responses to cancer. Dr. Delamarre's work has demonstrated that cancer-specific mutations, known as neo-antigens, which accumulate in tumors, possess high immunogenicity and can stimulate protective T cell responses against cancer. With the recent advancements in next-generation sequencing technologies, it has become possible to quickly and comprehensively discover cancer-specific mutations in individual patients. This presents an exciting opportunity to develop new strategies that specifically target neoantigens.
During her visit, Dr. Delamarre is also serving as Manlio Fusciello’s opponent on Friday 11th of August at 12:00 in Biocenter 2, Hall 2041 (Viikinkaari 5, Helsinki). The title of Fusciello’s dissertation is Cancer vaccines: anti-tumoral t cell therapy on demand and the public defence can be watched online via https://video.helsinki.fi/unitube/live-stream.html?room=l18
You are all welcome to both events!
Manlio
Fusciello and Vince
Cerullo
Special Seminar: Martin Korte
We have a great pleasure to welcome an outstanding guest speaker, prof. Martin Korte, Technische Universität Braunschweig, Germany, in our special seminar on Thursday August 10th at 15-16 am at BMH1, Kok 8-9.
Here Martin tells about his work and this talk:
What are your approaches to understand the influence of infections and inflammations for the progression of neurodegenerative diseases?
We use mice as a model system and approach our questions with cell biological, electrophysiological, imaging techniques and a behavioral analysis. We use influenca viruses of different strains to study long lasting effects of immune response in the brain (which is related to long/post covid).
How could an effective treatment look like in the future?
To prevent inflammatory processes inside the central nervous system might be an important step. But it could also well be that treatment is impossible, but that prevention is successful. Prevention could be life style factors, but also vaccination might be as important for our brains as it is for our immune system.
What will your talk be about?
The talk will cover common signaling mechanisms of the nervous-system and immune system. I will present data about the consequences of a sepsis for neurons in the central nervous system, the long-term effects in the CNS after an Influenza infection with different subtypes of the influenza virus and I will present data about the long-term consequences of maternal stress and early/late-life immune challenge in offspring