Events

August 25

Kliinisen mikrobiologian perjantaisarja: Klaus Hedman

My Life, My Viruses
Klaus Hedman, LKT, prof.emer., HY-Virologia & HUS Diagnostiikkakeskus






Start time: 25/08/2023 13:00
End time: 25/08/2023 14:00
Duration: 1 hour
Location:
Type: Seminar
Organization: HUS
Contact person: kira.virtanen@hus.fi,, sanni.paloviita@hus.fi, juulia.suominen@hus.fi
August 28

HiLIFE webinar / Biomedicum Helsinki seminar: Andreas Roos

Proteomic studies toward a better understanding of neuromuscular diseases
Andreas Roos studied biology with a main focus on molecular medicine and made a PhD in Human Genetics (focusing on the identification of genes causative for the manifestation of neuromuscular diseases), both at RWTH-Aachen University (Germany). During his postdoc period at the same University, he studied the nature of muscular diseases (mainly vacuolar myopathies) by applying electron microscopy and biochemical approaches. Afterwards, he became an independent group leader at the Leibniz-Institute of Analytical Science (Dortmund, Germany) applying different proteomic techniques to study the molecular etiology of neuromuscular diseases. Afterwards he became the Scientific Officer at the John Walton Muscular Dystrophy Research Centre in Newcastle (UK) where he continued his research activities. Since 2019 Andreas is the Research Coordinator and Scientific Officer of the Department of Neuropediatrics at the University Hospital Essen (Germany) where he still applies proteomic techniques to study the etiology of neuromuscular diseases on different level including the discovery of pathomechanisms, pre-clinical testing of drugs, identification of biomarkers and elucidation of the suitability of liquid biopsies.
Welcome to this exciting seminar!  

Marco Savarese
 
Selected publications:
Nguyen CDL, Jimenez-Moreno AC, Merker M, Bowers CJ, Nikolenko N, Hentschel A, Müntefering T, Isham A, Ruck T, Vorgerd M, Dobelmann V, Gourdon G, Schara-Schmidt U, Gangfuss A, Schröder C, Sickmann A, Gross C, Gorman G, Stenzel W, Kollipara L, Hathazi D, Spendiff S, Gagnon C, Preusse C, Duchesne E, Lochmüller H, Roos A. Periostin as a blood biomarker of muscle cell fibrosis, cardiomyopathy and disease severity in myotonic dystrophy type 1. J Neurol. 2023 Mar 9. [doi: 10.1007/s00415-023-11633-1; PMID: 36892629]
Schorling DC, Kölbel H, Hentschel A, Pechmann A, Meyer N, Wirth B, Rombo R; SMArtCARE consortium, Sickmann A, Kirschner J, Schara-Schmidt U, Lochmüller H*, Roos A*. Cathepsin D as biomarker in cerebrospinal fluid of nusinersen-treated patients with spinal muscular atrophy. Eur J Neurol. 2022 Jul 29(7):2084-2096. [doi: 10.1111/ene.15331; PMID: 35318785]
Preusse C, Marteau T, Fischer N, Hentschel A, Sickmann A, Lang S, Schneider U, Schara-Schmidt U, Meyer N, Ruck T, Dengler NF, Prudlo J, Dudesek A, Görl N, Allenbach Y, Benveniste O, Goebel HH, Dittmayer C, Stenzel W, Roos A. Endoplasmic reticulum-stress and unfolded protein response-activation in immune-mediated necrotizing myopathy. Brain Pathol. 2022 Jun 15:e13084. [doi: 10.1111/bpa.13084; PMID: 35703068]
Hathazi D, Cox D, D'Amico A, Tasca G, Charlton R, Carlier RY, Baumann J, Kollipara L, Zahedi RP, Feldmann I, Deleuze JF, Torella A, Cohn R, Robinson E, Ricci F, Jungbluth H, Fattori F, Boland A, O'Connor E, Horvath R, Barresi R, Lochmüller H, Urtizberea A, Jacquemont ML, Nelson I, Swan L, Bonne G, Roos A. INPP5K and SIL1 associated pathologies with overlapping clinical phenotypes converge through dysregulation of PHGDH. Brain. 2021 Sep 4;144(8):2427-2442. [doi: 10.1093/brain/awab133; PMID: 33792664]
Hentschel A, Czech A, Münchberg U, Freier E, Reimann J, Roos A. Protein Signature of Human Skin Fibroblasts Allows the Study of the Molecular Etiology of Rare Neurological Diseases; Orphanet J Rare Dis. 2021 Feb 9;16(1):73. [doi: 10.1186/s13023-020-01669-1; PMID: 33563298]
Kohlschmidt N, Elbracht M, Czech A, Häusler M, Phan V, Töpf A, Huang KT, Bartok A, Eggermann K, Zippel S, Eggermann T, Freier E, Groß C, Lochmüller H, Horvath R, Hajnóczky G, Weis J, Roos A. Molecular pathophysiology of human MICU1-deficiency; Neuropathol Appl Neurobiol. 2020. Online ahead of print. [doi: 10.1111/nan.12694; PMID: 33428302]
 
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University of Helsinki students please note: If you wish to obtain credits (DPBM, ILS) from this webinar series, please rename yourself in Zoom with first name + last name (do not use nickname/user ID/student number/just first name).
 
Upcoming seminars:
4.9.2023 Tamra Mendelson: Beauty and speciation in North American freshwater fishes
11.9.2023 Medix Prize. Topic area of the lecture: Stem cell technology in the field of diabetes research
25.9.2023 Alison Davis Rabosky: TBA



Start time: 28/08/2023 13:00
End time: 28/08/2023 14:00
Duration: 1 hour
Location: Biomedicum1, lecture hall 3, Haartmaninkatu 8, 00290 Helsinki
Type: Seminar
Organization: Biomedicum Helsinki
Contact person: hilife-seminars@helsinki.fi
August 30

Biostatistics drop-in workshop

Are you a researcher needing support with any statistical aspect of your work? The Biostatistics Consulting Service here at Meilahti Campus holds drop-in workshop sessions every other week to answer smaller questions about your analysis - solving a particular problem, how to get started, etc. We provide service in Finnish, English and Swedish.

The next workshop is on Wednesday 30th August, at 13:00-15:00 in Biomedicum 2B, in the Olohuone on floor 6. Come whenever you can. Note that you may end up waiting a while for your turn, especially early on in the session. We aim to spend no more than 15 minutes with each customer.
Bring:

·    your computer

·       your data

·       your questions

and we biostatisticians will be on hand to help and guide.
Registration is not required, but you can help us prepare for your questions by filling in this formThe workshops are open to any researcher at the university's Medical Faculty, HUS or FIMM.
The autumn's following sessions are planned for 13.9, 27.9, 11.10, 25.10, 8.11, 22.11 & 13.12 (not 6.12!).

For more in-depth questions, please book a one-on-one consultation session using this e-form where we will have time to go into more detail.

From the Biostatistics Team


Start time: 30/08/2023 13:00
End time: 30/08/2023 15:00
Duration: 2 hours
Location: Biomedicum 2, 6th floor lounge
Type: Other
Organization: Biostatistics Consulting Service
Contact person: biostat-consult@helsinki.fi
August 31

Dissertation: Maria Enlund-Cerullo

​Maria Enlund-Cerullo, University of Helsinki, Faculty of Medicine, Doctoral Program in Clinical Research
Vitamin D Metabolism in early childhood : Associations with genetic variants and biomarkers
Opponent: Professor Johanna Schleutker, University of Turku

Start time: 31/08/2023 13:00
End time: 31/08/2023 15:00
Duration: 2 hours
Location: Biomedicum1, lecture hall 3, Haartmaninkatu 8, 00290 Helsinki
Type: Dissertation
Organization: UH, Faculty of Medicine
Contact person: maria.enlund@helsinki.fi
September 01

Dissertation: Akseli Bonsdorff

​Akseli Bonsdorff, University of Helsinki, Faculty of Medicine, Doctoral Program in Clinical Research
Postoperative pancreatitis, prediction of pancreatic fistula, and mitigation of complications : novel insights into pancreatic surgery and pancreas transplantation

Opponent: assistant ptofessor Stefano Crippa, Vita Salute San Raffaele University, Milan, Italy



Start time: 01/09/2023 12:00
End time: 01/09/2023 14:00
Duration: 2 hours
Location: HUS Siltasairaala, Kruunuhakasali, Haartmaninkatu 4
Type: Dissertation
Organization: UH, Faculty of Medicine
Contact person: akseli.bonsdorff@helsinki.fi