Events

September 16

Dissertation: Maria Rautamo

​Maria Rautamo, University of Helsinki, Faculty of Pharmacy, Division of Pharmacology and Pharmacotherapy, Doctoral Programme in Drug Research
Age-appropriate oral pediatric formulations in hospitals : Evaluation of the suitability of printing technologies in meeting patient needs
Opponent: Assistant Professor Elisabeth Ruijgrok, Erasmus MC - Sophia Children's Hospital


Start time: 16/09/2022 13:00
End time: 16/09/2022 15:00
Duration: 2 hours
Location: Haartman Institute, lecture hall 2, Haartmaninkatu 3, 00290 Helsinki
Type: Dissertation
Organization: University of Helsinki
Contact person: maria.rautamo@helsinki.fi
September 16

Special Seminar by Dr. Laura Santambrogio

​Lymph as a conduit of organ homeostasis and immunosurveillance

Dr. Laura Santambrogio received her Ph.D. from Padua University in Italy, then trained as a post-doctoral Fellow at New York University and Harvard Medical School. 

Currently, she is Associate Director for Precision Immunology at the Englander Institute for Precision Medicine. She also holds appointments as Professor of Radiation Oncology, and Professor of Physiology and Biophysics at Weill Cornell Medicine. 

 

Her research focuses on two major areas:  

1) Analysis of the MHC II-restricted-peptidome during physiological and pathological conditions and its relevance to adaptive immune responses, and 

2) Analysis of lymphatic fluid: formation, composition and immunological role in physiological and pathological conditions.


 
https://radiationoncology.weillcornell.org/research/santambrogio-lab  

 

Recent publications: 

 

Clement CC, Osan J, Buque A, Nanaware PP, Chang YC, Perino G, Shetty M, Yamazaki T, Tsai WL, Urbanska AM, Calvo-Calle JM, Ramsamooj S, Ramsamooj S, Vergani D, Mieli-Vergani G, Terziroli Beretta-Piccoli B, Gadina M, Montagna C, Goncalves MD, Sallusto F, Galluzzi L, Soni RK, Stern LJ, Santambrogio L. PDIA3 epitope-driven immune autoreactivity contributes to hepatic damage in type 2 diabetes. Sci Immunol. :7 eabl3795, 2022. 

 

Santambrogio L. Molecular Determinants Regulating the Plasticity of the MHC Class II Immunopeptidome. Front Immunol. 13: 878271, 2022.  

 

Summers BD, Kim K, Clement CC, Khan Z, Thangaswamy S, McCright J, Maisel K, Zamora S, Quintero S, Racanelli AC, Redmond D, D'Armiento J, Yang J, Kuang A, Monticelli L, Kahn ML, Choi AMK, Santambrogio L, Reed HO. Lung lymphatic thrombosis and dysfunction caused by cigarette smoke exposure precedes emphysema in mice. Sci Rep. 12: 5012, 2022.  

 

Ambler W, Santambrogio L, Lu TT. Advances in understanding and examining lymphatic function: relevance for understanding autoimmunity. Curr Opin Rheumatol. 34: 133-138, 2022.  

 

Petroni G, Cantley LC, Santambrogio L, Formenti SC, Galluzzi L. Radiotherapy as a tool to elicit clinically actionable signalling pathways in cancer. Nat Rev Clin Oncol. 19: 114-131, 2022.  

 

Klionsky DJ, … Pietrocola F. Autophagy in major human diseases. EMBO J. 40: e108863, 2021.  

 

Warm welcome to the seminar! 

 

If you wish to meet the speaker, please contact saija.piiroinen@helsinki.fi  



Start time: 16/09/2022 14:00
End time: 16/09/2022 15:00
Duration:
Location: Biomedicum1, lecture hall 2, Haartmaninkatu 8, 00290 Helsinki
Type: Seminar
Organization: UH, Faculty of Medicine
Contact person: saija.piiroinen@helsinki.fi
September 19

HiLIFE webinar / Viikki Monday Seminar: Dani Dumitriu

The resilient mouse brain: from dendritic spines to circuits to wholebrain connectomics

Dani Dumitriu, MD, PhD, is a pediatrician and neuroscientist at Columbia University Irving Medical Center in New York City. She was born in Romania and grew up south of Stockholm, Sweden, prior to moving to the United States for her education. She completed her physician-scientist training, pediatric residency, and a pediatric environmental health fellowship at the Icahn School of Medicine at Mount Sinai, also in New York City, and was the first female to secure R01-level independent funding from the National Institutes of Health (NIH) during clinical training. She currently spends 20% time as a hospitalist in the Well Baby Nursery and 80% time conducting research into the mechanisms of emotional connection and resilience across species and investigational scales in her dual roles as Principal Investigator of the Developmental Origins of Resilience (DOOR) lab and as the newly announced Director of the Nurture Science Program. Her most recent research in animal models seeks to understand neuroconnectomic differences between stress-susceptible and stress-resilient mice, with a focus on pre-stress patterns in inbred mice housed in homogenous conditions. In a recent publication, her team identified both structural and functional differences in the prelimbic cortex to amygdala circuit mediating trait susceptibility to an acute social defeat stressor in C57 mice. Her most recent research in humans focuses on the effects of the COVID-19 pandemic on the generation born during these uncertain and changing times, and she is the founder and Chair of Columbia University's COVID-19 Mother Baby Outcomes (COMBO) Initiative. In a recent publication, her team showed that in utero exposure to the pandemic environment, but not to maternal SARS-CoV-2 infection during pregnancy, leads to small but significant decrements in motor and social skills at 6 months of age.  

@theDOORlab 

 

Welcome to this exciting seminar!  

Tuomas Aivelo 

 

Selected publications: 

Grossman YS, Fillinger C, Manganaro A, Voren G, Waldman R, Zou T, Janssen WG, Kenny PJ, *Dumitriu D. Structure and function differences in the prelimbic cortex to basolateral amygdala circuit mediate trait vulnerability in a novel model of acute social defeat stress in male mice. Neuropsychopharmacology 2022; Feb 47(3):788-799  

Bianco C, Sania A, Kyle MH, Beebe B, Barbosa J, Bence M, Coskun L, Fields A, Firestein MR, Goldman S, Hane A, Hott V, Hussain M, Hyman S, Lucchini M, Marsh R, Mollicone I, Myers M, Ofray D, Pini N, Rodriguez C, Shuffrey LC, Tottenham N, Welch MG, Fifer W, Monk C, *Dumitriu D, Amso D. Pandemic beyond the virus: maternal COVID-related postnatal stress is associated with infant temperament. Pediatric Research 2022 [April 20, 2022, online ahead of print]  

Shuffrey LC, Firestein MR, Kyle MH, Fields A, Alcántara C, Amso D, Austin J, Bain JM, Barbosa JR, Bence M, Bianco C, Fernández CR, Goldman S, Gyamfi-Bannerman C, Hott V, Hu Y, Hussain M, Factor-Litvak P, Lucchini M, Mandel A, Marsh R, McBrian D, Mourad M, Muhle R, Noble KG, Penn AA, Rodriguez C, Sania A, Silver WG, O’Reilly KC, Stockwell M, Tottenham N, Welch MG, Zork N, Fifer WP, M C, *Dumitriu D. Association of birth during the COVID-19 pandemic with neurodevelopmental status at 6 months in infants with and without in utero exposure to maternal SARS-CoV-2 infection. Journal of the American Medical Association (JAMA) Pediatrics; 176(6):e215563 [Jan 4, 2022, online ahead of print] 

Anderson KR, Harris JA, Ng L, Prins P, Memar S, Ljungquist B, Furth D, Williams RW, Ascoli GA, *Dumitriu D. (2021) Highlights from the era of open source web-based tools. Journal of Neuroscience 2021; 41(5): 927-936 

*Dumitriu D, Rodriguez A, Morrison JH. High-throughput, detailed, cell-specific neuroanatomy of dendritic spines using microinjection and confocal microscopy. Nature Protocols 2011; Aug 25; 6(9): 1391-411  

 

*** 

Start time: 19/09/2022 13:00
End time: 19/09/2022 14:00
Duration: 1 hour
Location: Biocenter 2, Lecture Hall 1041, Viikinkaari 5
Type: Seminar
Organization: Helsinki Institute of Life Science HiLIFE
Contact person: hilife-seminars@helsinki.fi
September 21

Studia Medicina: Tekoäly- isäntä vai renki lääketieteessä

Dosentti LT Kehittämisjohtaja (HUS) Visa Honkanen Tekoäly lääketieteessä – apuri vai uhka?
Dosentti LT Nina Linder Voiko tekoäly tunnistaa syövän?
Dosetntti LT Miikka Korja Tekoäy aivovammapotilaiden ennusteen arvioinnissa

Puheenjohtajana toimii professori Juha Sinisalo
Start time: 21/09/2022 17:00
End time: 21/09/2022 19:00
Duration: 1 hour
Location: Biomedicum1, lecture hall 1, Haartmaninkatu 8, 00290 Helsinki
Type: Education
Organization: Biomedicum Helsinki
Contact person: saatio@biomedicum.fi
September 23

Dissertation: Anna-Pauliina Iivonen

Anna-Pauliina Iivonen, University of Helsinki, Faculty of Medicine, Department of Physiology, Doctoral Programme in Biomedicine
Molecular Genetics of Rare Growth and Puberty Disorders in Finland

Opponent: professor Harri Niinikoski, University of Turku



Start time: 23/09/2022 12:00
End time: 23/09/2022 14:00
Duration: 2 hours
Location: Athena, Hall 107, Siltavuorenpenger 3 A, Helsinki
Type: Dissertation
Organization: UH, Faculty of Medicine
Contact person: anna-pauliina.iivonen@helsinki.fi