Events
HiLIFE / Biomedicum Helsinki seminar by lva Ivarsson: Towards a short-linear motif based map of the interactome
Ylva Ivarsson obtained a PhD in Biochemistry from Uppsala University in 2006, which was followed up by three international postdocs (Italy, Belgium and Canada) on the topics of protein folding and misfolding, protein-phospholipid interactions and short linear motif-based protein-protein interactions. Dr. Ivarsson was awarded a Young Investigator grant from the Swedish Research Council and returned to Sweden to start her independent lab in the Department of Chemistry - BMC, Uppsala University in July 2013. Dr. Ivarsson was tenured in 2018, and promoted to full professor of biochemistry in 2020. Since 2024 she is the head of the Biochemistry program at the Faculty of science and technology at Uppsala University. The Ivarsson lab combines biochemical and biophysical methods with bioinformatics and cell-based approach to explore interactions between modular domains and short linear motifs found in the intrinsically disordered regions of human and viral proteomes.
Welcome to this exciting seminar!
Markku Varjosalo
Selected publications:
Proteome-scale characterisation of motif-based interactome rewiring by disease mutations. Kliche et al, Mol Syst Biol. 2024. https://pubmed.ncbi.nlm.nih.gov/39009827/
Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs. Mihalic et al, Nat Comm. 2023. https://pubmed.ncbi.nlm.nih.gov/37100772/
Proteome-scale mapping of binding sites in the unstructured regions of the human proteome. Benz et al., Mol Syst Biol. 2022. https://pubmed.ncbi.nlm.nih.gov/35044719/
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University of Helsinki students please note: If you wish to obtain credits (DPBM, ILS) from this seminar series, please sign the participant list in the lecture hall or use your first name + last name in Zoom.
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