Events

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April 16

World Voice Day

World Voice Day is celebrated internationally on April 16th. This annual event highlights the importance of voice in people’s daily lives.

Hosted by the Department of Logopedics (Speech-Language Pathology) and students enrolled in the course “Voice and Voice Disorders,” this year’s World Voice Day event will take place as a Voice Fair including poster exhibition, workshops, and short lectures.


Our poster exhibition will highlight voice ergonomic risk factors such as stress and noise. In the interactive workshops, you can analyze your voice with professional tools and find out your fundamental frequency. The short lectures will cover voice health and preventive voice care.


This event is ideal for anyone keen on deepening their understanding of the human voice. It is particularly useful for professionals who rely heavily on their vocal abilities— university lecturers, students, teachers, healthcare workers, psychologists, speech-language pathologists, journalists, actors, and singers.


We hope to see you there!

Event language: Finnish

Link: https://worldvoiceday.org/
Start time: 16/04/2024 12:00
End time: 16/04/2024 16:00
Duration: 3 hours
Location: Terkko Health hub
Type: Other
Organization: University of Helsinki
Contact person: sofia.holmqvist-jamsen@helsinki.fi
Further information: https://terkko.fi/programmes-events/
Online meeting link:
April 17

Drug safety during pregnancy and lactation - 30 years of teratology information service in Finland

Finnish Teratology Information Service was established 30 years ago. To celebrate our journey, we will organize together with Finnish Society of Clinical Pharmacology and University of Helsinki 30th Anniversary Symposium ”Drug safety during pregnancy and lactation - 30 years of teratology information service in Finland” on 17th of April 2024 at Biomedicum, Helsinki.

 

Participation to Symposium is free of charge. Scientific programme will include presentations on drug utilization during pregnancy and breastfeeding, potential drug effects on fetal and neonatal health, and how to use secondary data and to apply new statistical methods in pharmacovigilance studies. Full programme is available here.

 

Symposium is open for all health care professionals but primarily targeted for clinicians caring for people and families who are planning a pregnancy or already are pregnant or breastfeeding.

 

We have applied 4 hours of theoretical training in the KOPI system for following specialties: Obstetrics and Gynaecology, Clinical Pharmacology and Pharmacotherapy, General Practice, Paediatrics, Public Health. There will be a possibility for online participation to those living outside the capital region. Kindly note that the certificate of attendance will only be provided to participants on site at Biomedicum.

 

Register yourself on Wednesday 3rd of April at the latest using the registration form. Online participants will receive a link to webinar 1-2 days before the Symposium to the email address they have provided at the registration form. In case you will need to cancel your participation after the registration, please fill out and submit a separate cancellation form as soon as possible so that we can arrange enough coffee and tea on site.

 

You are warmly welcome to join to celebrate our 30th Anniversary!


Start time: 17/04/2024 12:00
End time: 17/04/2024 16:00
Duration: 3 hours
Location: Biomedicum1, lecture hall 2, Haartmaninkatu 8, 00290 Helsinki
Type: Symposium
Organization: HUS
Contact person: petri.makela@helsinki.fi
Further information: https://urly.fi/3pVM
Online meeting link:
April 17

Biostatistics drop-in workshop

Are you a researcher needing support with any statistical aspect of your work? The Biostatistics Consulting Service here at Meilahti Campus holds drop-in workshop sessions every other week to answer smaller questions about your analysis - solving a particular problem, how to get started, etc. We provide service in Finnish, English and Swedish.

 

The next workshop is on Wednesday 17th April, at 13:00-15:00 in Biomedicum 2B, in the Olohuone on floor 6. Come whenever you can. Note that you may end up waiting a while for your turn, especially early on in the session. We aim to spend no more than 15 minutes with each customer.

 

Bring: 

·       your computer

·       your data

·       your questions

and we biostatisticians will be on hand to help and guide. 

 

Registration is not required, but you can help us prepare for your questions by filling in this form. The workshops are open to any researcher at the university's Medical Faculty, HUS or FIMM.

Sessions are planned to continue roughly every other week throughout the spring: 8.5 (N.B. not 1.5!) and 24.5.

 

For more in-depth questions, please book a one-on-one consultation session using this e-form where we will have time to go into more detail. 


Start time: 17/04/2024 13:00
End time: 17/04/2024 15:00
Duration: 2 hours
Location: Biomedicum 2, 6th floor lounge
Type: Other
Organization: Biostatistics Consulting Service
Contact person: biostat-consult@helsinki.fi
Further information: https://www.helsinki.fi/en/infrastructures/biostatistics-unit/consulting
Online meeting link:
April 17

iCAN science seminar: Dr. Florian Perner

Targeting oncogenic chromatin complexes: from mechanistic discoveries to clinical application

Speaker: Dr. Florian Perner, Hannover Medical School, Department of Hematology, Hemostaseology, Oncology and Stem Cell Transplantation

Dr. Perner received his doctorate from Otto-von-Guericke University Magdeburg in 2018. He is currently the PI of the Emmy-Noether Research Group “Translational Epigenetics”. The group studies epigenetic mechanisms in Acute Myeloid Leukemia, clonal hematopoiesis, and pre-leukemic conditions to understand the underlying basic biological principles and advance targeted epigenetic treatment strategies.

Dr. Florian Perner received the Artur-Pappenheim-Price from the German Society of Hematology and Oncology in October 2023. The Price honored his contribution to the understanding of the molecular mechanisms underlying responses of leukemia cells to treatment with inhibitors of the Menin-MLL1-Interaction.

Please see Dr. Perner’s CV for more information, and selected publications below.

Konstantin Matjusinski will host a student get-together with Dr. Perner after the talk. Please contact Konstantin (konstantin.matjusinski@helsinki.fi), if you are interested in joining.

If you wish to meet with Dr. Perner, please contact Mikko Myllymäki at mikko.myllymaki@helsinki.fi.

There will be coffee and pulla waiting for you prior to the seminar.


Selected publications (10 selected of last 5 years)

Perner F., Stein E.M., Wenge D.V., Singh S., Kim J., Apazidis A., Rahnamoun H., Anand D., Marinaccio C., Hatton C., Wen Y., Stone R.M., Schaller D., Mowla S., Xiao W.,10, Gamlen H.A., Stonestrom A.J., Persaud S., Ener E., Cutler J.A., Doench J.G., McGeehan G.M., Volkamer A., Chodera J.D., Nowak R.P., Fischer E.S., Levine R.L., Armstrong S.A., Cai S.F. MEN1 mutations mediate clinical resistance to Menin inhibition. 2023. Nature. 615(7954):913-919.

Soto-Feliciano Y.M.*, Sánchez-Rivera F.J.*, Perner F.*, Barrows D.W., Kastenhuber E.R., Ho Y.J., Carroll T., Xiong Y., Anand D., Soshnev A., Gates L., Beytagh M.C., Cheon D., Gu S., Liu X.S., Krivtsov A.V., Meneses M., de Stanchina E., Stone R.M., Armstrong S.A., Lowe S.W., and Allis C.D. A molecular switch between mammalian MLL complexes dictates response to Menin-MLL inhibition. 2023. Cancer Discovery, 13(1): p. 146-169. * authors contributed equally

Perner F., Schnoeder T.M., Xiong Y., Jayavelu A.K., Mashamba N., Tubio Santamaria N., Huber N., Todorova K., Hatton C., Perner B., Eifert T., Murphy C., Hartmann M., Hoell J.I., Schröder N., Brandt S., Hochhaus A., Mertens P.R., Mann M., Armstrong S.A., Mandinova A., Heidel F.H. YBX1 mediates translation of oncogenic transcripts to control cell competition in AML. 2021. Leukemia; in print

Perner F., Gadrey J.Y., Xiong Y., Hatton C., Eschle B.K., Weiss A., Stauffer F., Gaul C., Tiedt R., Perry J.A., Armstrong S.A., & Krivtsov A.V. Novel Inhibitors of the Histone-Methyltransferase DOT1L Show Potent Antileukemic Activity in Patient-derived Xenografts. 2020. Blood. doi:10.1182

Aubrey B.A., Cutler B.J., Bourgeois W., Donovan K.A., Gu S., Hatton C., Perlee S., Perner F., Rahnamoun H., Theall A.C.P., Henrich J.A., Zhu Q., Nowak R.P., Kim Y.J., Parvin S., Cremer A., Olsen S.N., Eleuteri N.A., Pikman Y., McGeehan G.M., Stegmaier K., Letai A., Fischer E.S., Liu X.S., & Armstrong S.A., IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemia. 2022. Nature Cancer, 3(5): p. 595-613.

Uckelmann H.J., Haarer E.L., Takeda R., Wong E.M., Hatton C., Marinaccio C., Perner F., Rajput M., Antonissen N.J.C., Wen Y., Yang L., Brunetti L., Chen C.W. & Armstrong S.A.. Mutant NPM1 directly regulates oncogenic transcription in acute myeloid leukemia. 2022. Cancer Discovery, CD-22-0366

Olsen S.N., Godfrey L., Healy J.P., Choi Y.A., Kai Y., Hatton C., Perner F., Haarer E.L., Nabet B., Yuan G.C. & Armstrong SA. MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape. 2022. Molecular Cell, 82(6): p. 1140-1155 e11.

Heikamp E.B., Henrich J.A., Perner F., Wong E.M., Hatton C., Wen Y., Barwe S.P., Gopalakrishnapillai A., Xu H., Uckelmann H.J., Takao S., Kazansky Y., Pikman Y., McGeehan G.M., Kolb E.A., Kentsis A. & Armstrong S.A. The Menin-MLL1 interaction is a molecular dependency in NUP98-rearranged AML. 2022. Blood. 139(6):894-906

Jayavelu, A.K., Schnoeder, T.M., Perner, F., Herzog, C., Meiler, A., Krishnamoorthy, G., Huber, N., Mohr, J., Edelmann-Stephan, B., Austin, R., Brandt, S., Palandri, F., Schroder, N., Isermann, B., Edlich, F., Sinha, A.U., Ungelenk, M., Hubner, C.A., Zeiser, R., Rahmig, S., Waskow, C., Coldham, I., Ernst, T., Hochhaus, A., Jilg, S., Jost, P. J., Mullally, A., Bullinger, L., Mertens, P.R., Lane, S.W., Mann, M., & Heidel, F.H. (2020). Splicing factor YBX1 mediates persistence of JAK2-mutated neoplasms. Nature, 588(7836), 157-163.

Krivtsov, A.V., Evans, K., Gadrey, J.Y., Eschle, B.K., Hatton, C., Uckelmann, H.J., Ross, K.N., Perner, F., Olsen, S.N., Pritchard, T., McDermott, L., Jones, C.D., Jing, D., Braytee, A., Chacon, D., Earley, E., McKeever, B.M., Claremon, D., Gifford, A.J., Lee, H.J., Teicher, B.A., Pimanda, J.E., Beck, D., Perry, J.A., Smith, M.A., McGeehan, G.M., Lock, R.B., & Armstrong, S.A. (2019). A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia. Cancer Cell, 36(6), 660-673.

Start time: 17/04/2024 13:30
End time: 17/04/2024 14:30
Duration:
Location: Biomedicum 1, seminar room 1-2
Type: Seminar
Organization: iCAN Flagship Team
Contact person: ican@helsinki.fi
Further information: https://ican.fi/news-events/ican-science-seminar-on-april-17-with-dr-florian-perner/
Online meeting link: https://helsinki.zoom.us/j/64804986682?pwd=ME8rOVhucnQ5YXE1VVdpck5BN25BZz09
April 18

Special semiar by prof Hong Qian

Unraveling leukemia niche contribution to therapy response and relapse – opportunity to identify new treatment options

Speaker: Prof. Hong Qian , Karolinska Institutet

Summary of the talk: The seminar will focus on leukemia microenvironment/niche contribution to the progression and therapy response of acute and chronic myeloid leukemia (AML and CML). The molecular and cellular alterations of the leukemia niches as well as the functional impact of the altered niche factors on leukemia-initiating stem cells will be presented/discussed during the talk. The talk will specifically discuss the role and molecular mechanism of two representative niche factors extracellular matrix molecule Lama4 and a chemokine CXCL14 in the proliferation and chemo-response of AML and CML-initiating stem cells.

Start time: 18/04/2024 13:00
End time: 18/04/2024 14:00
Duration: 1 hour
Location: Biomedicum 1, seminar room 1-2
Type: Seminar
Organization: University of Helsinki
Contact person: ella.sinervuori@helsinki.fi
Further information: https://ki.se/en/research/groups/leukemia-niche-hong-qian-group
Online meeting link: