HiLIFE webinar / Viikki Monday Seminar: Hilal Lashuel
Dr. Hilal A. Lashuel received his B.Sc. degree in chemistry from the City University of New York in 1994 and completed his doctoral studies at Texas A&M University and the Scripps Research Institute in 2000. In 2001, he moved to Harvard Medical School and the Brigham and Women’s Hospital as a research fellow in the Center for Neurologic Diseases and was later promoted to an instructor in neurology at Harvard Medical School. In 2005, Dr. Lashuel moved Switzerland to join the Brain Mind Institute at the Swiss Federal Institute of Technology Lausanne (EPFL) as a tenure-track assistant professor in neurosciences, where he currently is an associate professor of life sciences and the director of the laboratory of molecular and chemical biology of neurodegeneration.
Dr. Lashuel is an expert in biochemistry of neurodegeneration-related aggregation prone proteins, including alpha-synuclein, tau, huntingtin. He has more than 120 peer-review publications in high-quality peer-review journals. He holds three patents on novel strategies for preventing protein aggregation and treating autoimmune and inflammatory diseases. Dr. Lashuel is the recipient of Human Science Frontiers young investigator research award, the European Research Council (ERC) starting independent researcher grant and the ERC proof of concept award (2013), Young Global Leader by the World Economic Forum (2012), the Michael J. Fox Foundation Parkinson’s disease Grand Challenge Award, Kuwait Prize in fundamental Sciences (Biological Sciences, 2018), Takreem Foundation Scientific and Technological Achievements Award (2019), and H. Martin Friedman Distinguished Lecture (2020). In addition, Hilal Lashuel is the founder of ND BioSciences, a biotechnology startup established in 2019 developing technologies and services for the development of early diagnostics and therapies for neurodegenerative diseases, such as Parkinson’s and Alzheimer’s diseases.
Welcome to this exciting seminar!
NOTE: For PhD (or Master’s) students, there are few spaces available for student lunch with Dr Lashuel at Viikki. Please email firstname.lastname@example.org if you want to join!
Riguet, N., Mahul-Mellier, AL., Maharjan, N. et al (2021).. Nuclear and cytoplasmic huntingtin inclusions exhibit distinct biochemical composition, interactome and ultrastructural properties. Nat Commun 12, 6579. https://doi.org/10.1038/s41467-021-26684-z
Lashuel, H. A. (2021). Rethinking protein aggregation and drug discovery in neurodegenerative diseases. Current Opinion in Chemical Biology 64: 67-75. https://doi.org/10.1016/j.cbpa.2021.05.006
Mahul-Mellier, A.-L., Burtscher, J., Maharjan, N., Weerens, L., Croisier, M., Kuttler, F., Leleu, M., Knott, G. W., & Lashuel, H. A. (2020). The process of Lewy Body Formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration. Proceedings of the National Academy of Sciences, 117(9), 4971–4982. https://www.pnas.org/doi/full/10.1073/pnas.1913904117
University of Helsinki students please note: If you wish to obtain credits (DPBM, ILS) from this webinar series, please rename yourself in Zoom with first name + last name (do not use nickname/user ID/student number/just first name).
CancerBio Summer School&Cancer IO Sebinar: Douglas Hanahan
D. Hanahan. Hallmarks of Cancer: New Dimensions. Cancer Discovery. 2022-01-01. DOI : 10.1158/2159-8290.CD-21-1059.
S. Saghafinia; K. Homicsko; A. Di Domenico; S. Wullschleger; A. Perren, et al., D. Hanahan. Cancer Cells Retrace a Stepwise Differentiation Program during Malignant Progression. Cancer Discovery. 2021-10-01. DOI : 10.1158/2159-8290.CD-20-1637.
Q. Zeng; I. P. Michael; P. Zhang; S. Saghafinia; G. Knott, et al., D. Hanahan. Synaptic proximity enables NMDAR signalling to promote brain metastasis. Nature. 2019-09-26. DOI : 10.1038/s41586-019-1576-6.
K. Shchors; A. Massaras; D. Hanahan. Dual Targeting of the Autophagic Regulatory Circuitry in Gliomas with Repurposed Drugs Elicits Cell-Lethal Autophagy and Therapeutic Benefit. Cancer Cell. 2015. DOI : 10.1016/j.ccell.2015.08.012.
A. Sadanandam; C. A. Lyssiotis; K. Homicsko; E. A. Collisson; W. J. Gibb, et al., D. Hanahan. A colorectal cancer classification system that associates cellular phenotype and responses to therapy. Nature Medicine. 2013. DOI : 10.1038/nm.3175.
Find out more information on Professor Hanahan's research and recent publications:
Docentship lecture: Takashi Namba
"Adult neurogenesis in the human hippocampus: Death of a dogma or not?”
Length is 30min, after which there is discussion, and then the audience will evaluate the lecture.
Faculty of Medicine Honorary Doctors' Symposium
The symposium is organized as a part of the XV Conferment of the Faculty and features all the 10 honorary doctors participating in the festivities. For a detailed programme and a presentation of the international speakers, all of whom are experts in their respective fields, please see the attached programme.
The Symposium can be included in the theoretical studies of most fields of specialty.