Events
Dissertation: Helinä Kahma
Opponent: Assitant Professor Youssef Daali, University of Geneva
HiLIFE / Biomedicum Helsinki by research director Alain Destexhe
Research Director Alain Destexhe from the Institut NeuroPSI, CNRS Université Paris-Saclay, France, will give a talk in the HiLIFE Seminar Series on November 3rd, 13.00-14.00.
The research conducted in Alain
Destexhe’s laboratory stands at the interface between several disciplines, such
as biophysics, physics, computer science and neuroscience. The themes
investigated range from the microscopic (single neurons) to the macroscopic
(networks or populations of neurons) aspects of the central nervous system
function. At the single cell level, we use theoretical methods and
computer-based simulation techniques to explore the complex behavior of
cortical and thalamic neurons and understand their integrative properties. At
the network level, we try to understand the collective behavior of neuronal
populations, and how information is processed and represented. We also study
the genesis of sleep rhythms, their physiological role and their perversion
into pathological rhythms such as epileptic seizures. Welcome to this exciting seminar! Sheng H Wang Selected publications: Contreras, D., Destexhe, A., Sejnowski, T.J. and Steriade, M.
Control of spatiotemporal coherence of a thalamic oscillation by
corticothalamic feedback. Science 274: 771-774, 1996. Destexhe, A., Rudolph, M. and Paré, D. The high-conductance state
of neocortical neurons in vivo. Nature Reviews Neurosci. 4 : 739-751, 2003. Destexhe, A. and Contreras, D. Neuronal computations with
stochastic network states. Science 314: 85-90, 2006 Rebollo, B., Telenczuk, B., Navarro-Guzman, A., Destexhe, A. and
Sanchez-Vives, M.V. Modulation of intercolumnar synchronization by endogeneous
electric fields in cerebral cortex. Science Advances 7: eabc7772, 2021 Sacha, M., Tesler, F., Cofre, R. and Destexhe, A. A
computational approach to evaluate how molecular mechanisms impact large-scale
brain activity. Nature Computational Sci. 5: 405-417, 2025. Zerlaut, Y. and Destexhe, A. Enhanced responsiveness and low-level
awareness in stochastic network states. Neuron 94: 1002-1009, 2017.